SALLA DISEASE - CLINICAL AND BIOCHEMICAL FINDINGS

Molecular Pathogenesis of Salla Disease

Clinical, hematologic, and biochemical findings in cattle infected with lumpy skin disease during an outbreak in southwest Iran

This study was performed to determine the clinical, hematologic, and biochemical findings in animals affected with lumpy skin disease (LSD) in southwest Iran. Sixty cattle with LSD were included in this study and compared with 20 healthy ones as the control group. The disease was diagnosed based on clinical examination and confirmed by polymerase chain reaction analysis of the blood samples. Th...

Diagnostic challenges in Salla disease

Sialic acid storage disease (Salla disease) is an autosomal recessive disorder caused by mutations in a lysosomal sialic acid export protein, SLC17A5 (OMIM #604369). This disorder was initially described in Northern Finland but more recently has been reported in patients of other ethnicities. We describe the clinical presentation and the neuroimaging findings of two non-Finnish children where a...

Brain involvement in Salla disease.

BACKGROUND AND PURPOSE Our purpose was to document the nature and progression of brain abnormalities in Salla disease, a lysosomal storage disorder, with MR imaging. METHODS Fifteen patients aged 1 month to 43 years underwent 26 brain MR examinations. In 10 examinations, signal intensity was measured and compared with that of healthy volunteers of comparable ages. RESULTS MR images of a 1-m...

Study of the Clinical and Radiologic findings of Middle East Respiratory Syndrome and Coronavirus Disease-2019

Aim and Background: Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV-2) is a single-strand RNA, β‐coronavirus with mostly respiratory symptoms responsible for Corona Virus Disease (COVID-19), which causes a pandemic worldwide. This novel coronavirus is associated with severe pneumonia and Acute Respiratory Distress Syndrome (ARDS). Middle East Respiratory Syndrome (MERS-CoV) is another ...